Table 1: Baseline demographic and clinical characteristics.
|
Overall n = 51 |
Disease severity, n (%) |
|||
|
Mild |
Severe |
P value |
||
|
30 (59) |
21 (41) |
|||
|
Demographic |
||||
|
Age, years median (Q1, Q3) |
48 (30, 66) |
40 (27, 58) |
61 (49, 76) |
0.0067 |
|
≤ 40 years n (%) |
18 (35) |
15 (50) |
3(14) |
0.0085 |
|
41-60 years n (%) |
16 (31) |
9 (30) |
7 (33) |
0.8025 |
|
> 60 years n (%) |
17 (33) |
6 (20) |
11 (52) |
0.0159 |
|
Gender, n (%) |
||||
|
Female |
28 (55) |
21 (70) |
7 (33) |
0.0096 |
|
Male |
23 (45) |
9 (30) |
14 (67) |
0.0096 |
|
BMI*, kg/m2, median (Q1, Q3) |
28 (26, 32) |
28 (23, 31) |
29 (26, 32) |
0.61 |
|
Smoking past or present, n (%) |
11 (22) |
4 (14) |
7 (32) |
0.1211 |
|
Health care worker, n (%) |
3 (6) |
2 (7) |
1 (6) |
0.7263 |
|
Comorbidities, n (%) |
||||
|
Hypertension |
21 (41) |
6 (21) |
15 (68) |
0.0006 |
|
Diabetes |
9 (18) |
1 (3) |
8 (36) |
0.0022 |
|
Cardio vascular disease |
9 (18) |
0 (0) |
9 (41) |
0.0001 |
|
Chronic lung diseases (COPD, BA, ILD) |
8 (16) |
6 (21) |
2 (9) |
0.2584 |
|
Malignancy |
1 (2) |
0 (0) |
1 (6) |
0.246 |
|
Chronic kidney disease |
6 (12) |
0 (0) |
6 (27) |
0.0027 |
|
CTD**/immunosuppressed |
4 (8) |
1 (3) |
3 (14) |
0.1802 |
|
≥ 2 comorbidities, n (%) |
20 (39) |
6 (21) |
14 (64) |
0.0018 |
|
Symptomatology, n (%) |
||||
|
Fever |
32 (63) |
15 (52) |
17 (77) |
0.0614 |
|
Cough |
35 (69) |
19 (66) |
16 (72) |
0.5823 |
|
Dyspnea |
14 (27) |
6 (21) |
8 (36) |
0.2149 |
|
Hemoptysis |
1 (2) |
0 (0) |
1 (6) |
0.246 |
|
Sore throat |
21 (41) |
13 (45) |
8 (36) |
0.5418 |
|
Fatigue |
34 (67) |
19 (66) |
15 (68) |
0.8418 |
|
Anorexia |
19 (37) |
11 (38) |
8 (36) |
0.9124 |
|
Diarrhea |
6 (12) |
3 (10) |
3 (14) |
0.7188 |
|
Nausea/vomiting |
2 (4) |
0 (0) |
2 (9) |
0.0969 |
|
Anosmia |
8 (16) |
6 (21) |
2 (9) |
0.2584 |
|
Ageusia |
11 (22) |
8 (28) |
3 (14) |
0.2301 |
|
Headache |
15 (29) |
8 (28) |
7 (32) |
0.7414 |
|
Vital signs |
||||
|
Temperature °C, median (Q1,Q3) |
37.4 (36.6, 38) |
37 (36.8, 37.6) |
37.8 (37.4, 38.7) |
0.00008 |
|
< 38 (%) |
38 (75) |
26 (90) |
12 (55) |
0.0043 |
|
≥ 38 (%) |
13 (25) |
3 (10) |
10 (45) |
0.0043 |
|
MAP***, mmHg, median (Q1,Q3) |
86 (79, 95) |
85 (77, 97) |
88 (81, 92) |
0.3173 |
|
Heart rate, per minute, median (Q1,Q3) |
80 (74, 88) |
80 (74, 88) |
81 (74, 94) |
0.4839 |
|
Respiratory rate, per minute, median (Q1,Q3) |
20 (20, 20) |
20 (20, 20) |
20 (20, 26) |
0.0734 |
|
Oxygen saturation, % median (Q1,Q3) |
97 (95, 99) |
98 (97, 99) |
95 (91, 97) |
0.0003 |
*BMI: Body Mass Index; **CTD: Connective Tissue Disease; ***MAP: Mean Arterial Blood Pressure.
Sum of decimals in percentage values have been rounded to whole number where appropriate. The sum of percentages may not be equal to 100.