Table 1: Main maternal, gestational, birth and neonatal clinical and biological variables. Figures expressed as number (percentages), except when stated otherwise.

 

Mothers (n = 106)

Caucasian

AIDS

Substance abuse

Cigarettes

Methadone

Heroin

Cocaine

Alcohol

Others

Multidrug (2 or more drugs)

HCV co-infection

 

84 (79.2)

5 (4.7)

38 (35.8)

31 (29.2)

10 (9.4)

4 (3.8)

2 (1.9)

3 (2.8)

6 (5.7)

7 (6.6)

42 (39.6)

Gestation and delivery (n = 114)

Mother’s age, mean (SD)

30.5 (5.2)

ARV treatment during pregnancy

 

No treatment

ZDV monotherapy

HAART

From 1st trimester

PI-based

NNRTI-based

CD4+ cell count at delivery (cells/mm3), mean (SD)

Undetectable viremia at delivery

Elective caesarian section

6 (5.3)

8 (7.0)

100 (87.7)

63 (55.3)

48 (42.1)

56 (49.1)

578 (340)

84 (73.7)

83 (72.8)

Intrapartum ARV treatment

 

No treatment

Intravenous ZDV

7 (6.1)

103 (90.4)

Newborn (n = 118)

 

Female

Apgar below 8 at 1 or 5 minutes

Gestational age (weeks), mean (SD)

Birth weight (g), mean (SD)

53 (44.9)

7 (5.9)

37.6 (1.1)

2880 (440)

ARV prophylaxis in newborn

 

Oral ZDV     

Others

107 (90.7)

11 (9.3)

 

ARV: Antiretroviral; HCV: Hepatitis C virus; ZDV: Zidovudine; HAART: Highly active antiretroviral therapy; PI: Protease inhibitor; NNRTI: Non-nucleoside reverse transcriptase inhibitors.