Study

Outcome Measure

Findings

Van Wely, et al. (Year)

Live Birth Rate (LBR)

Higher with epididymal sperm compared to testicular sperm (OR = 1.82, 95% CI: 1.05-3.67)

Chen, et al. (1995)

Pregnancy Rate

Favorable pregnancy rate (68.0% versus 64.2%, P = 0.02) with testicular sperm

Nicopoullos, et al. (2004)

Clinical Pregnancy Rate

No significant difference between acquired and congenital obstructive azoospermia (OA) groups (RR = 1.03; 95% CI: 0.75-1.31)

Nicopoullos, et al. (2004)

Live Birth Rate

No significant difference between acquired and congenital OA groups (RR = 1.03; 95% CI: 0.81-1.31)

Nicopoullos, et al. (2004)

Fertilization Rate

Higher in acquired OA group (RR = 0.92; 95% CI: 0.84-1; P = 0.05)

Nicopoullos, et al. (2004)

Miscarriage Rate

Higher in congenital OA group (RR = 2.67)

Esteves, et al. (Year)

Live Birth Rate

No difference according to OA etiology: 32% (vasectomy), 43.8% (infection), and 33.3% (congenital)

Esteves, et al. (Year)

Miscarriage Rate

No difference among the groups: 26.9% (vasectomy), 20.0% (infection), and 25% (congenital)

Esteves, et al. (Year)

Neonatal Outcomes

Mean neonatal weight: 2777.6 ± 673.9 g, mean gestational age: 37.0 ± 2.3 weeks

Esteves, et al. (Year)

Adverse Events

One perinatal death due to renal agenesis in CBAVD group, one case of hypospadias (1.5%) in the whole series