Table 2: Comparison of the specificity of anti-MSP-119 antibodies between females and males, defined as the proportion of serum samples (at a dilution of 1:250) able to inhibit the binding of mouse monoclonal antibodies (of known binding specificities) to MSP-119 in a competition ELISA.

 

 

Mab

 

Reduction in Mab binding (%)

  SEX

Female

N = 84

n (%)

Male

N = 72

n (%)

c2 )P(

 

12.1

41 (49)

17 (23)

10.54 (0.001)

12.8

35 (42)

19 (26)

 4.00 (0.046)

1.00E + 01

37 (44)

18 (25)

 6.16 (0.013)

7.5

32 (38)

15 (21)

 5.49 (0.019)

8 A 12

33 (39)

15 (21)

 6.20 (0.013)

2F10

30 (36)

13 (18)

 6.05 (0.014)