All Patients

(N = 305)

G1

(N = 45)

G2

(N = 30)

G3

(N = 43)

G4

(N = 187)

Age, years, mean ±SD

62.3 ± 10.7

64.5 ± 11.6

66.4 ± 8.3

62.2 ± 10

61.2 ± 10.8

Age ≥ 75 years, n (%)

41 (13.4)

11 (24.4) ^*

4 (13.3) ^**

6 (13,9) ^***

20 (10.7)

Male gender, n (%)

244 (80)

36 (80)

25 (83)

38 (88)

145 (77.5)

Diabetes, n (%)

170 (55.7)

27 (60)

18 (60)

24 (55.8)

101 (54)

Currentsmoker, n (%)

113 (37)

17 (37.7)

12 (40)

16 (37)

68 (36.3)

Hypertension, n (%)

145 (47.5)

27 (60)

13 (43.3)

14 (32.5)

91 (48.6)

Hyperlipidemia, n (%)

109 (35.7)

13 (28.8)

12 (40)

15 (34.8)

69 (36.9)

BMI, mean ±SD

26.4 ± 2.8

26.5 ± 2.9

26.2 ± 2.7

26.1 ± 2.6

26.5 ± 2.9

Prior MI, n (%)

78 (25.6)

21 (46.6) ^*

4 (13.3)

8 (18.6)

45 (24)

Prior PCI, n (%)

92 (30.2)

13 (28.8)

6 (20)

12 (27.9)

61 (32.6)

Prior CABG, n (%)

16 (5.2)

6 (13.3) ^*

0

5 (11.6)

5 (26)

Prior stroke, n (%)

9 (3)

2 (4.4)

1 (3.3)

1 (2.3)

5 (2.6)

PAD, n (%)

18 (5.9)

3 (6.7)

0

3 (7)

12 (6.4)

CKD, n (%)

36 (11.8)

6 (13.3)

5 (16.6) ^**

7 (16.2) ^***

18 (9.6)

LVEF, % ± SD

50.4 ± 8.4

48.9 ± 8.5

48.5 ± 10

49.9 ± 7.6

51.1 ± 8.3

LVEF ≤ 40%, n (%)

40 (13.1)

9 (20)

4 (13.3)

3 (7)

24 (12.8)

ClinicalPresentation

SCAD, n (%)

102 (33.4)

20 (44.4)

11 (34.3)

7 (16.3)

64 (34.2)

STEMI, n (%)

91 (29.8)

11 (24.4)

10 (33.3)

19 (44.1)

51 (27.2)

NSTEMI, n (%)

81 (26.6)

10 (22.2)

6 (20)

12 (27.9)

53 (28.3)

Unstableangina, n (%)

31 (9.2)

4 (9)

3 (10)

5 (11.6)

19 (10.3)

Medicalinsurance, n (%)

266 (87.2)

39 (86.7)

27 (90)

36 (83.7)

164 (87.7)