Table 4: Unadjusted and adjusted hazard ratio for pre-procedural TIMI 0-2 flow vs. pre-procedural TIMI 3 flow.

Pre TIMI 0-2 Unadjusted hazard ratio (95% CI) p-value Adjusted hazard ratio (95% CI) p-value
≤ 30 day MACE 1.587 [1.132-2.225] 0.007 1.281 [0.894-1.836] 0.177
≤ 30 day CVD 1.681 [1.142-2.476] 0.009 1.233 [0.816-1.862] 0.32
1-year MACE 1.198 [0.975-1.473] 0.086 1.111 [0.893-1.382] 0.334
> 30 day MACE 0.977 [0.752-1.270] 0.864 0.948 [0.720-1.249] 0.705
1-year all-cause death 1.300 [1.011-1.672] 0.041 1.125 [0.861-1.470] 0.387
1-year CVD 1.496 [1.084-2.063] 0.014 1.265 [0.903-1.773] 0.172
> 30 day CVD 0.984 [0.570-1.696] 0.953 1.029 [0.589-1.798] 0.921
MI 0.922 [0.486-1.748] 0.803 1.129 [0.529-2.410] 0.753
RePCI (TVR/TLR) 0.911 [0.633-1.311] 0.616 0.923 [0.632-1.346] 0.923

TIMI: Thrombolysis in Myocardial Infarction; MACE: Major Adverse Cardiac Events; CVD: Cardiovascular Death; TVR: Target Vessel Revascularization; TLR: Target Lesion Revascularization; RePCI: Recurrent Percutaneous Coronary Intervention.

MACE is defined as the composite of the death of any cause, recurrence of MI, TLR, TVR, and CABG. Adjustment : Age, sex , history of hypertension, diabetes, dyslipidemia, and smoking, killip I-II vs. III-IV, multi-vessel disease, lesion type A/B1 vs. B2/C, target vessels, Door to balloon time, CK-MB, Creatinine, use of aspirin, clopidogrel, beta-blocker, RAS blocker, statin at admission.