Table 3: Prescription treatments for GSM.

Vaginal Estrogen Ring

Estring (7.5 mcg estradiol released qd)

 

Inserted by pt or clinician every 90 days

 

 

Vaginal Estrogen Insert

Vagifem/Yuvafem (10 mcg estradiol)

 

Insert 1 tablet vaginally qhs for 2 weeks, then twice weekly

 

Imvexxy (4 mcg and 10 mcg estradiol)

 

Insert vaginally qhs for 2 weeks, then twice weekly

 

 

Vaginal Estrogen Cream

Estrace (100 mcg estradiol per gram)

 

Insert 0.5 to 1 gm vaginally qhs for 2 weeks, then twice a week

 

Premarin (0.625 mg conjugated estrogen per gram)

 

Insert 0.5 to 1 gm vaginally qhs for 2 weeks, then twice a week

 

 

Ospemifene (Osphena) - SERM

60 mg daily oral tablet

 

 

Prasterone (Intrarosa) - DHEA

6.5 mg nightly intravaginal suppository