Table 3: Performance of screening by different combinations of biomarkers.
|
Detection rate (%) for a given false positive rate (FPR) |
|
||
PTD < 34 wks |
PTD 34-37 wks |
PTD < 37 wks |
||
FPR 10% |
FPR 10% |
FPR 10% |
||
PAPP-A MoM |
78.6 |
20.0 |
82.1 |
|
AFP MoM |
85.7 |
74 |
79 |
|
β-hCG MoM |
14.3 |
0 |
2.6 |
|
Cx |
85.7 |
80.0 |
82.1 |
|
UtA PI MoM |
0 |
4.0 |
17.9 |
|
Risk factor + PAPP-A MoM |
89.1 |
81.1 |
84.2 |
|
AFP MoM |
92.9 |
76.0 |
79.5 |
|
Cx |
85.7 |
84.0 |
82.1 |
|
Cx + AFP MoM |
78.6 |
88.0 |
89.7 |
|
Cx + AFP MoM + PAPP-A MoM |
92.9 |
89.0 |
91.1 |
|
FPR - false positive rate |
|
|