Table 4: Multivariate analysis details: Variables associated with an increased recurrence.

 

Variable

 

HR (CI 95%)

 

p

 

cN; N + vs. N0

 

HR 2.82 (CI 1.21-6.80)

 

p = 0.017

 

TIL changes pre and post NAC; Decrease or non-changes vs. increase

 

HR 3.10 (CI 1.05-9.66)

 

p = 0.040

 

ypT; tumor residual > 2 cm vs. < 2 cm

 

HR 2.92 (CI 1.51-5.25)

 

p = 0.001

 

Low TIL vs. High TIL in residual disease

 

HR 1.59 (CI 0.70-3.59)

 

p = 0.263

 

Low TIL vs. High TIL in core biopsy

 

HR 1.51 (CI 0.31-7.29)

 

p = 0.604