Variable

HR (CI 95%)

p

Clinical stage TNM III vs. II

HR 2.22 (CI 1.51-4.21)

p = 0.001

cT ; > 2 cm vs. < 2 cm

HR 1.76 (CI 0.24-12.77)

p = 0.567

cN; cN + vs. cN0

HR 2.50 (CI 1.39-4.49)

p = 0.020

Grade III vs. I-II in core biopsy

HR 1.39 (CI 0.79-2.44)

p = 0.243

Low TIL vs. High TIL in core biopsy

HR 3.44 (CI 1.78-6.65)

p = 0.001

TIL changes pre and post NAC; Decrease or non-changes vs. increase

HR 4.01 (CI 1.69-9.59)

p = 0.002

Pathologic complete response; Non-pCR vs. pCR

HR 2.89 (CI 1.56-5.36)

p = 0.001

Residual disease stage ypTNM II-III vs. I

HR 4.28 (CI 1.91-9.59)

p = 0.001

ypT; residual breast tumor > 2 cm vs. < 2 cm

HR 3.01 (CI 1.66-5.44)

p = 0.002

ypN; ypN + vs. ypN0

HR 3.66 (CI 2.19-6.12)

p = 0.001

Low TIL vs. High TIL in residual disease

HR 4.27 (CI 2.29-7.98)

p = 0.001