Table 1b: Lactobacilli of doctor’s biome colon health.
(registered trademarks of DuPont-Danisco)
Lactobacillus acidophilus La-14®
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This strain is a specially selected strain of Lb. acidophilus. Well-suited for intestinal survival it has a high tolerance to gastrointestinal conditions (acid, bile, pepsin and pancreatin). LA-14 also has strong adhesion to intestinal cell lines. LA-14 may influence immune regulation as demonstrated by the induction of IL-12 and moderate induction of tumor necrosis factors in vitro. |
Lactobacillus brevis Lbr-35 |
This is a specially selected strain of Lb. brevis that could be part of a multiple strain custom blend with a variety of excipients. |
Lactobacillus bulgaricus Lb-87
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This strain is a specially selected strain of Lb. bulgaricus. L. bulgaricus metabolizes and produces D (-)-lactic acid from four sugars: Lactose, glucose, fructose and mannose. LB-87 has the ability to rapidly convert lactose into lactic acid. LB-87 also has the ability to convert lactose into lactate, aiding in lactose digestion. |
Lactobacillus casei Lc-11® |
This strain is a specially selected strain of Lb. casei. LC-11 is well suited for intestinal survival and functionality. It is highly tolerant of acid and bile. LC-11 adheres strongly to intestinal Caco--2 cell lines and it inhibits common pathogens. |
Lactobacillus gasseri Lg-36 |
This strain is a specially selected strain of Lb. gasseri that could be part of a multiple strain custom blend with a variety of excipients. |
Lactobacillus paracasei Lpc-37® |
This strain is a specially selected strain of Lb. paracasei. Lpc-37 displayed in vitro inhibition of selected pathogens including Salmonella typhimurium, Staphylococcus aureus, Escherichia coli and Listeria monocytogenes. A five-strain formulation including L. paracasei (Lpc-37) was found to maintain and more rapidly restore microbiota after antibiotic treatment. LPC-37 is well-suited for intestinal survival, it has a high tolerance to gastrointestinal conditions (acid and bile). |
Lactobacillus plantarum Lp-115®
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This strain is a specially selected strain of Lb. plantarum. In vitro studies have shown that L. plantarum (Lp-115) is extremely resistant to low pH conditions and survives the presence of bile at concentrations present in the duodenum. Lp-115 displayed in vitro inhibition of selected pathogens including Salmonella typhimurium, Staphylococcus aureus, Escherichia coli and Listeria monocytogenes. LP-115 is well-suited for intestinal survival; it has a high tolerance to gastrointestinal conditions (acid, bile, pepsin and pancreatin) and has strong adhesion to intestinal cell lines. LP-115 may improve specific immune response, as demonstrated in a human clinical study. |
Lactobacillus reuteri 1E1 |
This is a specially selected strain of Lactobacillus reuteri that could be part of a multiple strain custom blend with a variety of excipients. |
Lactobacillus rhamnosus Lr-32®
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This strain is a specially selected strain of Lb. rhamnosus. L. rhamnosus (Lr-32) has shown anti-inflammatory properties, as demonstrated through significant protection against TNBS induced colitis in an animal model. L. rhamnosus (Lr-32) may influence immune regulation, as demonstrated by the increased induction of IL-10 in vitro. |
Lactobacillus salivarius Ls-33®
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This is a specially selected strain of Lb. salivarius. LS-33 is well-suited for intestinal survival, it has a high tolerance to gastrointestinal conditions (acid, bile, pepsin and pancreatin). LS-33 has a strong adhesion to intestinal cell lines, and ability to inhibit common pathogens. It also has a beneficial modulation of immune functions, it may influence immune regulation, as demonstrated by increased induction of IL-10 in vitro. |