Table 3: Comparison of chronic diseases between Covid-19 breakthrough infections and no Covid-19 breakthrough infections in vaccinated people and calculation of relative risks.
Risk factors chronic diseases* according to who, ICD-10 groups |
Covid-19 breakthrough infections in vaccinated people N =30 |
No Covid-19 breakthrough infections in vaccinated people N =1970 |
Statistical significance |
Relative risk (RR) |
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-I Infectious |
0 |
20 (0.5) |
Fisher exact test = 1. NS |
RR = 0 (CI 95%: Infinity, 0) Protection factor effectively |
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-II Neoplasms |
0 |
153(3) |
Fisher exact test = 0.1834. NS |
RR = 0 (CI 95%: Infinity, 0) Protection factor effectively |
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-III Diseases of the blood |
2 (3) |
87 (2) |
Fisher exact test = 0.6561. NS |
RR =1.39 (CI 95%: 0, 561299.91). Weak risk |
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-IV Endocrine |
13 (16) |
553 (12) |
X2 = 1.8161 p = 0.177783. NS |
RR =1.5 (CI 95%: 0.76, 2.96). Weak risk |
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-V Mental |
4 (5) |
627 (13) |
X2 = 4.635 p = 0.031326 Significant at p < 0.05 |
RR = 0.35 (CI 95%: 0.98, 0.12). Protection factor effectively |
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-VI-VIII Nervous and Senses |
10 (13) |
367 (8) |
X2 = 2.7479 p = 0.097384. NS |
RR = 1.73 (CI 95%: 0.82, 3.63). Moderate risk |
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-IX Circulatory system |
10 (13) |
867 (18) |
X2 = 1.6789 p = 0.195064. NS |
RR= 0.65 (CI 95%: 1.35, 0.31). True benefits |
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-X Respiratory system |
3 (4) |
393 (8) |
X2 = 2.1172 p = 0.145648. NS |
RR = 0.44 (CI 95%: 1.59, 0.12). Protection factor effectively |
|||
-XI Digestive system |
12 (15) |
387 (8) |
X2 = 5.335 p = 0.020901 Significant at p < 0.05 |
RR = 2.03 (CI 95%: 1.05, 3.93). Moderate risk |
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-XII Diseases of the skin |
0 |
120 (2) |
Fisher exact test = 0.2684. NS |
RR= 0 (CI 95%: Infinity, 0). Protection factor effectively |
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-XIII Musculo-skeletal |
19 (24) |
720 (15) |
X2 = 4.9532 p = 0.026042. Significant at p < 0.05 |
RR= 1.77 (CI 95%: 1.03, 3.04). Moderate risk |
|||
|
-XIV Genitourinary |
6 (7) |
406 (9) |
X2 = 0.0962. p = 0.756492. NS |
RR= 0.88 (CI 95%: 8.58, 0.09). Not significant |
||
|
-XVII Congenital malformations |
0 |
20 (0.5) |
Fisher exact test = 1. NS |
RR= 0 (CI 95%: Infinity, 0). Protection factor effectively |
||
|
-XIX Injury, poisoning and certain other consequences of external causes |
0 |
20 (0.5) |
Fisher exact test = 1. NS |
RR= 0 (CI 95%: Infinity, 0). Protection factor effectively |
||
|
-XXI Factors influencing health status |
0 |
13 (0.5) |
Fisher exact test = 1. NS |
RR = 0 (CI 95%: Infinity, 0). Protection factor effectively |
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|
Total chronic diseases** |
79 (100) |
4753 (100) |
- |
- |
( ): Denotes percentages; *Patients could have more than one chronic disease. The percentages are over the total of chronic diseases; NS: Not significant at p < 0.05; RR: Relative risk