Table 1: Demographic data and clinical characteristics of type 2 diabetic patients by the level of Lp(a).
Items |
Lp (a) ≥ 75 nmol/L |
Lp (a) < 75 nmol/L |
All T2DM patients |
P value |
n (%) |
72 (31.2) |
159 (68.8) |
231 |
- |
Age (years) |
61 (55-65) |
58 (53-63) |
59 (53-64) |
0.014 |
Sex ratio (M/W) |
1.76 |
1.23 |
1.38 |
0.141 |
Current smokers, n (%) |
13 (18.1) |
11 (6.9) |
24 (10.4) |
0.012 |
Postmenopausal status n (%) |
22 (84.6) |
52 (73.2) |
74 (76.2) |
0.186 |
Body mass index (kg/m2) |
26.8 (22.6-31.4) |
20.4 (19.2-22.7) |
21.4 (19.5-25.4) |
< 0.001 |
≤ 30 n (%) |
51 (70.8) |
157 (98.7) |
208 (90) |
< 0.001 |
> 30 n (%) |
21 (29.2) |
2 (1.3) |
23 (10) |
|
Waist circumference (cm) Men |
94 (89-101) |
89 (82-93) |
90 (85-98) |
0.001 |
Waist circumference (cm) women |
90 (78-98) |
78 (72-84) |
78 (73.5-89) |
< 0.001 |
Diabetes duration (years) |
11 (6-19.5) |
10 (6-15) |
10 ( 6-15 |
0.053 |
< 5 years n (%) |
15 (20.8) |
39 (24.5) |
54 23.4) |
0.327 |
6 à 10 years n (%) |
20 (27.8) |
55 (34.6) |
75 (32.5) |
|
> 10 years n (%) |
37 (51.4) |
65 (40.9) |
102 (44.2) |
|
Hypertension n (%) |
39 (54.2) |
48 (30.2) |
87 (37.7) |
< 0.001 |
Metabolic syndrome n (%) |
33 (45.8) |
33 (20.8) |
66 (28.5) |
< 0.001 |
Nephropathy n (%) |
6 (8.3) |
10 (6.3) |
16 (6.9) |
0.377 |
Retinopathy n (%) |
16 (22.2) |
25 (15.7) |
41 (17.7) |
0.156 |
Foot ulcer n (%) |
10 (13.9) |
2 (1.3) |
12 (5.2) |
< 0.001 |
Neuropathy n (%) |
33 (45.8) |
42 (26.4) |
75 (32.5) |
0.003 |
Previousmyocardial infarction n (%) |
16 (22.2) |
8 (5.0) |
24 (10.4) |
< 0.001 |
Cerebrovascular accident n (%) |
8 (11.1) |
2 (1.3) |
10 (4.3) |
0.002 |
Peripheral arterial disease n (%) |
8 (11.1) |
1 (0.6) |
9 (3.9) |
< 0.01 |
Treated with oral drugs |
41 (56.9) |
78 (49.05) |
119 (51.5) |
0.07 |
Treated with Insulin |
7 (9.7) |
34 (21.4) |
41 (17.7) |
0.03 |
Data is shown as median and IQR (interquartile range) or proportions (%).
(N: Number of patients tested). Lp(a): Lipoprotein (a). Significant (P < 0.05)