Table 1: Demographic data and clinical characteristics of type 2 diabetic patients by the level of Lp(a).

Items

Lp (a) ≥ 75 nmol/L

Lp (a) < 75 nmol/L

All T2DM patients

P value

n (%)

72 (31.2)

159 (68.8)

231

-

Age (years)

61 (55-65)

58 (53-63)

59 (53-64)

0.014

 Sex ratio (M/W)

1.76

1.23

1.38

0.141

Current smokers, n (%)

13 (18.1)

11 (6.9)

24 (10.4)

0.012

Postmenopausal status n (%)

22 (84.6)

52 (73.2)

74 (76.2)

0.186

Body mass index (kg/m2)

26.8 (22.6-31.4)

20.4 (19.2-22.7)

21.4

(19.5-25.4)

< 0.001

30 n (%)

51 (70.8)

157 (98.7)

208 (90)

 

< 0.001

> 30 n (%)

21 (29.2)

2 (1.3)

23 (10)

Waist circumference

 (cm) Men

94 (89-101)

89 (82-93)

90 (85-98)

0.001

Waist circumference

(cm) women

90 (78-98)

78 (72-84)

78 (73.5-89)

< 0.001

Diabetes duration (years)

11 (6-19.5)

10 (6-15)

10 ( 6-15

0.053

< 5 years n (%)

15 (20.8)

39 (24.5)

54 23.4)

0.327

6 à 10 years n (%)

20 (27.8)

55 (34.6)

75 (32.5)

> 10 years n (%)

37 (51.4)

65 (40.9)

102 (44.2)

Hypertension n (%)

39 (54.2)

48 (30.2)

87 (37.7)

< 0.001

Metabolic syndrome

n (%)

33 (45.8)

33 (20.8)

66 (28.5)

< 0.001

Nephropathy n (%)

6 (8.3)

10 (6.3)

16 (6.9)

0.377

Retinopathy n (%)

16 (22.2)

25 (15.7)

41 (17.7)

0.156

Foot ulcer n (%)

10 (13.9)

2 (1.3)

12 (5.2)

< 0.001

Neuropathy n (%)

33 (45.8)

42 (26.4)

75 (32.5)

0.003

Previousmyocardial infarction n (%)

16 (22.2)

8 (5.0)

24 (10.4)

< 0.001

Cerebrovascular accident n (%)

8 (11.1)

2 (1.3)

10 (4.3)

0.002

Peripheral arterial disease n (%)

8 (11.1)

1 (0.6)

9 (3.9)

< 0.01

Treated with oral drugs

41 (56.9)

78 (49.05)

119 (51.5)

0.07

Treated with Insulin

7 (9.7)

34 (21.4)

41 (17.7)

0.03

Data is shown as median and IQR (interquartile range) or proportions (%).
(N: Number of patients tested). Lp(a): Lipoprotein (a). Significant (P < 0.05)