Table 1: Patient characteristics, extent and location of the neoplasm, and treatment received according to evolution.
>
Variables |
Study group n = 138 |
CR n = 77 |
NCR n = 61 |
p-value |
>
Age, median (range) |
62 (54-71) |
61 (54-70) |
65 (54-72) |
0.565 |
>
Sex (% male) |
121 (87.7) |
68 (88.3) |
53 (86.9) |
0.800 |
>
Neoplasm location |
|
|
|
0.469 |
>
Oral cavity |
26 (18.8) |
16 (20.8) |
10 (16.4) |
|
>
Pharynx |
29 (21.0) |
14 (18.2) |
15 (24.6) |
|
>
Larynx |
50 (36.2) |
28 (36.4) |
22 (36.1) |
|
>
Cavum |
8 (5.8) |
5 (6.5) |
4 (6.6) |
|
>
Paranasal sinuses |
10 (7.2) |
5 (6.5) |
5 (8.2) |
|
>
Thyroid |
2 (1.4) |
1 (1.3) |
1 (1.6) |
|
>
Multiple |
1 (0.7) |
1 (1.3) |
0 (0.0) |
|
>
Primary unknown |
12 (8.7) |
7 (9.1) |
5 (8.2) |
|
>
Histology |
|
|
|
< 0.001 |
>
Squamous cell carcinoma |
87 (63.0) |
57 (74.0) |
30 (49.2) |
|
>
Small cell carcinoma |
4 (2.9) |
3 (3.9) |
1 (1.6) |
|
>
Epidermoid |
29 (21.0) |
5 (6.5) |
24 (39.3) |
|
>
In situ |
9 (6.5) |
9 (11.7) |
0 (0.0) |
|
>
Undifferentiated |
7 (5.1) |
1 (1.3) |
6 (9.8) |
|
>
Adenoid cystic carcinoma |
2 (1.4) |
2 (2.6) |
0 (0.0) |
|
>
AJCC stage 6th edition |
|
|
|
< 0.001 |
>
I |
10 (7.2) |
10 (13.0) |
0 (0.0) |
|
>
II |
10 (7.2) |
10 (13.0) |
0 (0.0) |
|
>
III |
38 (27.5) |
33 (42.9) |
5 (8.2) |
|
>
IV |
80 (58.0) |
24 (31.2) |
56 (91.8) |
|
>
Surgery |
65 (47.1) |
35 (45.5) |
30 (50.0) |
0.597 |
>
Chemotherapy |
110 (79.7) |
68 (88.3) |
42 (68.9) |
0.005 |
>
Radiotherapy |
91 (65.9) |
59 (76.6) |
32 (54.2) |
0.006 |
Values as median (interquartile range) or n (percentage); CR: Complete Remission; NCR: Non Complete Remission; AJCC: American Joint Committee on Cancer. p-value: Calculated with the chi-square test or Mann-Whitney test.