Table 1: Training set of Artemisinin-Dipetidyl Vinyl Sulfone (AVSHx) inhibitors used for QSAR models preparation.
Training Set | R1 | R2 | R3 | (µM) |
AVSH1 | CH2Ph | H | Ph | 16.5 |
AVSH2 Phe-Phe | CH2Ph | CH2Ph | Ph | 22.4 |
AVSH3 Phe-hPhe | CH2CH2Ph | CH2Ph | Ph | 9.22 |
AVSH4 Leu-hPhe | CH2CH2Ph | CH2CH(CH3)2 | Ph | 4.95 |
AVSH5 Phe-hPhe | CH2CH2Ph | CH2Ph | CH3 | 21.6 |
AVSH6 Leu-hPhe | CH2CH2Ph | CH2CH(CH3)2 | CH3 | 0.35 |