Table 1: Training set of Artemisinin-Dipetidyl Vinyl Sulfone (AVSHx) inhibitors used for QSAR models preparation.

Training Set R1 R2 R3 I C 50 exp (µM)
AVSH1 CH2Ph H Ph 16.5
AVSH2 Phe-Phe CH2Ph CH2Ph Ph 22.4
AVSH3 Phe-hPhe CH2CH2Ph CH2Ph Ph 9.22
AVSH4 Leu-hPhe CH2CH2Ph CH2CH(CH3)2 Ph 4.95
AVSH5 Phe-hPhe CH2CH2Ph CH2Ph CH3 21.6
AVSH6 Leu-hPhe CH2CH2Ph CH2CH(CH3)2 CH3 0.35