Table 3: Fertility-sparing treatment cohort (N = 33), demographics and clinical characteristics of patients with continued fertility sparing treatment versus subsequent definitive treatment.

 

Overall N = 33

Fertility Sparing Treatment Continued n = 27 (81.8%)

Subsequent Definitive Treatment n = 6 (18.2%)

P value

Age at diagnosis (yrs), Median (IQR)

 

34.4 (30.2-36.5)

 

34.4 (30.3-36.5)

 

32.3 (29.2-38.2)

0.76

Stage, N (%) IA1

IA2 IB1

 

25 (75.8)

< 5

< 5

 

19 (70.4)

< 5

< 5

 

6 (100.0)

< 5

< 5

0.43†

Histology, N (%) Adenocarcinoma

Squamous

14 (42.4)

19 (57.6)

10 (37.0)

17 (63.0)

< 5

< 5

0.36†

Race/ethnicity, N (%) Asian

Hispanic White

Non-Hispanic White Other/Unknown

 

7 (21.2)

5 (15.2)

19 (57.6)

< 5

 

6 (22.2)

< 5

15 (55.6)

< 5

 

< 5

< 5

< 5

< 5

> 0.99†

BMI (kg/m2), Median (IQR)

26.4 (21.8-29.0)

27.6 (22.8-32.3)

21.4 (18.1-26.4)

0.05

Neighborhood Deprivation Index, N (%)

Q1 (Least Deprived) Q2

Q3

Q4 (Most Deprived)

 

 

5 (15.2)

16 (48.5)

< 5

8 (24.2)

 

 

< 5

13 (48.2)

< 5

7 (25.9)

 

 

< 5

< 5

< 5

< 5

> 0.99†

Parity, N (%) Nulliparous Parous

 

19 (57.6)

14 (42.4)

 

16 (59.3)

11 (40.7)

 

< 5

< 5

 

>0.99†

Wilcoxon performed on continuous variables that are not normally distributed. Some cells may have exact frequencies and percentages suppressed due to small cell size.

†: Fisher’s Exact performed on categorical variables with cell counts less than 5.