Table 1: Overall cohort (N = 128), demographics and clinical characteristics of patients with fertility sparing versus definitive treatment.

 

Overall N = 128

Fertility Sparing Treatment

n = 33 (25.8%)

Definitive treatment n = 95 (74.2%)

P value

Age at diagnosis (yrs), Median (IQR)

 

36.5 (34.0-39.8)

 

34.4 (30.2-36.5)

 

37.2 (35.0-40.4)

< 0.001

Stage, N (%) IA1

IA2 IB1

IB2

 

55 (43.0)

16 (12.5)

51 (39.8)

6 (4.7)

 

25 (75.8)

< 5

< 5

< 5

 

30 (31.6)

12 (12.6)

47 (49.5)

6 (6.3)

< 0.001†

Histology, N (%) Adenocarcinoma

Squamous

 

65 (50.8)

63 (49.2)

 

14 (42.4)

19 (57.6)

 

51 (53.7)

44 (46.3)

0.27*

Race/ethnicity, N (%) Asian

Hispanic White Non-Hispanic Black

Non-Hispanic White Other/Unknown

 

26 (20.3)

15 (11.7)

7 (5.5)

67 (52.3)

13 (10.2)

 

7 (21.2)

5 (15.2)

< 5

19 (57.6)

< 5

 

19 (20.0)

10 (10.5)

7 (7.4)

48 (50.5)

11 (11.6)

0.48†

BMI (kg/m2), Median (IQR)

27.5 (22.6-31.6)

26.4 (21.8-29.0)

27.8 (23.0-31.8)

0.13

Neighborhood Deprivation Index, N (%)

Q1 (Least Deprived) Q2

Q3

Q4 (Most Deprived)

 

 

19 (14.8)

48 (37.5)

35 (27.3)

26 (20.3)

 

 

5 (15.2)

16 (48.5)

< 5

8 (24.2)

 

 

14 (14.7)

32 (33.7)

31 (32.6)

18 (19.0)

0.12†

Parity, N (%) Nulliparous Parous

 

42 (32.8)

86 (67.2)

 

19 (57.6)

14 (42.4)

 

23 (24.2)

72 (75.8)

<0.001*

Years of Diagnosis, N (%) 2011-2013

2014-2017

2018-2020

 

29 (22.7)

56 (43.8)

43 (33.6)

 

6 (18.2)

13 (39.4)

14 (42.4)

 

23 (24.1)

43 (45.3)

29 (30.5)

0.43

Wilcoxon performed on continuous variables that are not normally distributed. Some cells may have exact frequencies and percentages suppressed due to small cell size.

*: Chi-Square performed on categorical variables

†: Fisher’s Exact performed on categorical variables with cell counts less than 5.