Table 1: Overall cohort (N = 128), demographics and clinical characteristics of patients with fertility sparing versus definitive treatment.
|
|
Overall N = 128 |
Fertility Sparing Treatment n = 33 (25.8%) |
Definitive treatment n = 95 (74.2%) |
P value |
|
Age at diagnosis (yrs), Median (IQR) |
36.5 (34.0-39.8) |
34.4 (30.2-36.5) |
37.2 (35.0-40.4) |
< 0.001 |
|
Stage, N (%) IA1 IA2 IB1 IB2 |
55 (43.0) 16 (12.5) 51 (39.8) 6 (4.7) |
25 (75.8) < 5 < 5 < 5 |
30 (31.6) 12 (12.6) 47 (49.5) 6 (6.3) |
< 0.001† |
|
Histology, N (%) Adenocarcinoma Squamous |
65 (50.8) 63 (49.2) |
14 (42.4) 19 (57.6) |
51 (53.7) 44 (46.3) |
0.27* |
|
Race/ethnicity, N (%) Asian Hispanic White Non-Hispanic Black Non-Hispanic White Other/Unknown |
26 (20.3) 15 (11.7) 7 (5.5) 67 (52.3) 13 (10.2) |
7 (21.2) 5 (15.2) < 5 19 (57.6) < 5 |
19 (20.0) 10 (10.5) 7 (7.4) 48 (50.5) 11 (11.6) |
0.48† |
|
BMI (kg/m2), Median (IQR) |
27.5 (22.6-31.6) |
26.4 (21.8-29.0) |
27.8 (23.0-31.8) |
0.13 |
|
Neighborhood Deprivation Index, N (%) Q1 (Least Deprived) Q2 Q3 Q4 (Most Deprived) |
19 (14.8) 48 (37.5) 35 (27.3) 26 (20.3) |
5 (15.2) 16 (48.5) < 5 8 (24.2) |
14 (14.7) 32 (33.7) 31 (32.6) 18 (19.0) |
0.12† |
|
Parity, N (%) Nulliparous Parous |
42 (32.8) 86 (67.2) |
19 (57.6) 14 (42.4) |
23 (24.2) 72 (75.8) |
<0.001* |
|
Years of Diagnosis, N (%) 2011-2013 2014-2017 2018-2020 |
29 (22.7) 56 (43.8) 43 (33.6) |
6 (18.2) 13 (39.4) 14 (42.4) |
23 (24.1) 43 (45.3) 29 (30.5) |
0.43 |
Wilcoxon performed on continuous variables that are not normally distributed. Some cells may have exact frequencies and percentages suppressed due to small cell size.
*: Chi-Square performed on categorical variables
†: Fisher’s Exact performed on categorical variables with cell counts less than 5.