Table 2: Results of GO enrichment analysis of common up and down regulated genes.
GO Term |
Reference genes in category |
Description |
DGEs count |
Gene names |
0051248 |
20 |
Negative regulation of protein metabolic process |
8 |
CTSZ, GPX1, GSTP1, IGFBP3, ITM2C, MAGEA2, MAGEA3, MECOM |
0010941 |
30 |
Regulation of cell death |
10 |
CTSZ, GPX1, GSTP1, IGFBP3, MAGEA3, MALT1, MECOM, MSX1, PAX8, TRIM2 |
0030162 |
6 |
Regulation of proteolysis |
4 |
CTSZ, GPX1, MAGEA3, MALT1 |
0032269 |
17 |
Negative regulation of cellular protein metabolic process |
7 |
CTSZ, GPX1, GSTP1, IGFBP3, MAGEA2, MAGEA3, MECOM |
0043281 |
4 |
Regulation of cysteine-type endopeptidase activity involved in apoptotic process |
7 |
GPX1, MAGEA3, MALT1 |
0045861 |
4 |
Negative regulation of proteolysis |
3 |
CTSZ, GPX1, MAGEA3 |
0052548 |
4 |
Regulation of endopeptidase activity |
3 |
GPX1, MAGEA3, MALT1 |
2000116 |
4 |
Regulation of cysteine-type endopeptidase activity |
3 |
GPX1, MAGEA3, MALT1 |
0043067 |
29 |
Regulation of programmed cell death |
9 |
GPX1, GSTP1, IGFBP3, MAGEA3, MALT1, MECOM, MSX1, PAX8, TRIM2 |
0019904 |
12 |
Protein domain specific binding |
5 |
CCN1, CXADR, GPX1, SCNN1A, TCEAL9 |
0004602 |
2 |
Glutathione peroxidase activity |
2 |
GPX1, GSTP1 |
0070062 |
49 |
Extracellular exosome |
14 |
ACSL4, AKR1B1, CRISPLD1, CTSZ, FSTL1, GREB1, GSTP1, IGFBP7, ITM2C, LDHB, MSN, PSAT1, RAB34, SCNN1A |
0043230 |
50 |
Extracellular organelle |
14 |
ACSL4, AKR1B1, CRISPLD1, CTSZ, FSTL1, GREB1, GSTP1, IGFBP7, ITM2C, LDHB, MSN, PSAT1, RAB34, SCNN1A |
1903561 |
50 |
Extracellular vesicle |
14 |
ACSL4, AKR1B1, CRISPLD1, CTSZ, FSTL1, GREB1, GSTP1, IGFBP7, ITM2C, LDHB, MSN, PSAT1, RAB34, SCNN1A |
0044432 |
28 |
Endoplasmic reticulum part |
9 |
ACSL4, COL9A2, CTSZ, FADS2, FSTL1, GJA1, IGFBP3, IGFBP7, RCN1 |