Covariate

Level

Hazard Ration (95% CI)

HR p-value

Overall

Local therapy

0.81 (0.73-0.90)

< 0.001

Local therapy + Hormone

0.61 (0.54-0.68)

< 0.001

Lumpectomy Alone

Ref

Subgroup^*: ER/PR+

Local therapy vs. Lumpectomy Alone

0.88 (0.77-1.00)

0.046

Local therapy + Hormone vs. Lumpectomy Alone

0.60 (0.53-0.69)

< 0.001

Local therapy vs. Local therapy + Hormone

1.45 (1.30-1.62)

< 0.001

Subgroup^*: ER/PR-

Local therapy vs. Lumpectomy Alone

0.61 (0.48-0.78)

< 0.001

Local therapy + Hormone vs. Lumpectomy Alone

0.53 (0.41-0.68)

< 0.001

Local therapy vs. Local therapy + Hormone

1.15 (0.93-1.42)

0.188