Table 4: Volumetric brain analyses.

Brain Volumes (mm3)

Control mice (n =7)

AVD-deficient mice (n = 8)

White Matter Structures#

 

 

Anterior commissure

1.59 ± 0.03

1.60 ± 0.03

CC/Ext capsule

9.43 ± 0.11

9.29 ± 0.26

Fimbria

1.97 ± 0.02

1.91 ± 0.04

Internal capsule

1.67 ± 0.01

1.62 ± 0.05

Brain Regions#

 

 

Amygdala

9.53 ± 0.08

9.46 ± 0.23

Basal forebrain

9.68 ± 0.11

9.76 ± 0.15

Rest of midbrain

10.49 ± 0.09

10.29 ± 0.18

Brain stem

48.11 ± 0.62

46.19 ± 1.36

Caudate putamen

20.63 ± 0.23

20.55 ± 0.36

Central grey

3.39 ± 0.05

3.39 ± 0.07

Cerebellum

41.76 ± 0.95

40.76 ± 1.14

Globus pallidus

2.12 ± 0.02

2.08 ± 0.05

Hippocampus

22.98 ± 0.12

22.92 ± 0.37

Hypothalamus

9.47 ± 0.12

9.47 ± 0.18

Inferior colliculi

4.19 ± 0.06

4.06 ± 0.10

Superior colliculi

6.58 ± 0.10

6.55 ± 0.14

Neocortex

109.02 ± 1.13

109.36 ± 1.98

Thalamus

20.85 ± 0.26

20.85 ± 0.46

Total Brain volume$

387.35 ± 3.90

383.69 ± 7.90

#The volumes of white matter structures and segmented brain regions were calculated using the registration of segmented 3D atlas
$Total brain volume was calculated excluding the olfactory bulbs.
There were no significant differences of brain volumes between control and AVD-deficient mice.