Table 4: Volumetric brain analyses.
Brain Volumes (mm3) |
Control mice (n =7) |
AVD-deficient mice (n = 8) |
White Matter Structures# |
|
|
Anterior commissure |
1.59 ± 0.03 |
1.60 ± 0.03 |
CC/Ext capsule |
9.43 ± 0.11 |
9.29 ± 0.26 |
Fimbria |
1.97 ± 0.02 |
1.91 ± 0.04 |
Internal capsule |
1.67 ± 0.01 |
1.62 ± 0.05 |
Brain Regions# |
|
|
Amygdala |
9.53 ± 0.08 |
9.46 ± 0.23 |
Basal forebrain |
9.68 ± 0.11 |
9.76 ± 0.15 |
Rest of midbrain |
10.49 ± 0.09 |
10.29 ± 0.18 |
Brain stem |
48.11 ± 0.62 |
46.19 ± 1.36 |
Caudate putamen |
20.63 ± 0.23 |
20.55 ± 0.36 |
Central grey |
3.39 ± 0.05 |
3.39 ± 0.07 |
Cerebellum |
41.76 ± 0.95 |
40.76 ± 1.14 |
Globus pallidus |
2.12 ± 0.02 |
2.08 ± 0.05 |
Hippocampus |
22.98 ± 0.12 |
22.92 ± 0.37 |
Hypothalamus |
9.47 ± 0.12 |
9.47 ± 0.18 |
Inferior colliculi |
4.19 ± 0.06 |
4.06 ± 0.10 |
Superior colliculi |
6.58 ± 0.10 |
6.55 ± 0.14 |
Neocortex |
109.02 ± 1.13 |
109.36 ± 1.98 |
Thalamus |
20.85 ± 0.26 |
20.85 ± 0.46 |
Total Brain volume$ |
387.35 ± 3.90 |
383.69 ± 7.90 |
#The volumes of white matter structures and segmented brain regions were calculated using the registration of segmented 3D atlas
$Total brain volume was calculated excluding the olfactory bulbs.
There were no significant differences of brain volumes between control and AVD-deficient mice.