The top 6 most significant bio functions identified using Ingenuity Pathway Analysis, with detailed lists of biological processes that may be impacted by the dysregulated proteins within each bio function to p < 0.001. If a biological process was identified in two bio functions, it is still only listed once..

Table 3: The top 6 most significant bio functions identified using Ingenuity Pathway Analysis, with detailed lists of biological processes that may be impacted by the dysregulated proteins within each bio function to p < 0.001. If a biological process was identified in two bio functions, it is still only listed once.

Bio Functions	No. of Molecules
Small Molecule Biochemistry	19
- release of neurotransmitter	6
- release of amino acids	5
- metabolism of amino acids	5
- modification of L-glutamic acid	2
- transport of amino acids	4
- uptake of amino acids	3
- synthesis of amino acids	3
- metabolism of glutamine	2
- release of L-glutamic acid	3
- accumulation of ceramide	2
- secretion of catecholamine	3
Cell-To-Cell Signaling and Interaction	17
- binding of lymphoma cell lines	3
- plasticity of synapse	4
- quantity of synapse	3
- binding of carcinoma cell lines	2
- neurotransmission	6
Molecular Transport	17
- secretion of molecule	9
- transport of molecule	13
Cellular Assembly and Organisation	15
- quantity of vesicles	5
- quantity of synaptic vesicles	3
- retraction of dendrites	2
- translocation of vesicles	2
- retraction of neuritis	3
- remodeling of actin filaments	2
- quantity of synapse	3
- enlargement of endosomes	2
- secretion of vesicles	2
Amino Acid Metabolism	10
Behaviour	10
- emotional behavior	7
- contextual learning	2
- contextual conditioning	4
- conditioning	5
- cued conditioning	3
- fear	3
- long-term memory	3
- active avoidance response	2
- discrimination	2
- startle response	3
- spatial learning	4