Table 2: Significant (p < 0.01) canonical pathways identified using Ingenuity Pathway Analysis in order of significance. Ratio values are the number of proteins dysregulated out of the number of proteins in the pathway.
Canonical Pathways |
p-value |
Ratio values |
g-glutamyl Cycle |
0.0004 |
0.13 |
Glutamine Biosynthesis I |
0.002 |
1.00 |
D-mannose Degradation |
0.002 |
1.00 |
Epithelial Adherens Junction Signaling |
0.003 |
0.02 |
Glutamate Dependent Acid Resistance |
0.004 |
0.50 |
Tight Junction Signaling |
0.005 |
0.02 |
Sertoli Cell-Sertoli Cell Junction Signaling |
0.005 |
0.02 |
Glutamate Receptor Signaling |
0.006 |
0.04 |
Glutathione Biosynthesis |
0.006 |
0.33 |
GABA Receptor Signaling |
0.008 |
0.03 |
Agrin Interactions at Neuromuscular Junction |
0.008 |
0.03 |