Table 1: Proteins that were found to be significantly different between control and AVD- deficient male BALB/c mice (p < 0.05) in order from lowest p-value to highest.
Protein No. |
Accession No. |
Gene Name |
Protein Name |
Pept-ides |
% Cov |
Mean Cont |
Mean AVD |
FC |
P-value |
422 |
Q9WV80 |
Snx1 |
Sorting nexin-1 |
3 |
5.75 |
1.0001 |
1.2605 |
1.2603 |
0.001 |
1007 |
Q99LI8 |
Hgs |
Hepatocyte growth factor- regulated tyrosine kinase substrate |
4 |
3.23 |
1.0047 |
0.7119 |
-1.4112 |
0.002 |
1374 |
Q56A07 |
Scn2b |
Sodium channel subunit beta-2 |
2 |
5.58 |
0.8280 |
1.2618 |
1.5238 |
0.002 |
1063 |
P63325 |
Rps10 |
40S ribosomal protein S10 |
2 |
13.94 |
1.2953 |
2.3771 |
1.8351 |
0.003 |
673 |
O54774 |
Ap3d1 |
AP-3 complex subunit delta-1 |
6 |
3.67 |
1.2388 |
0.6064 |
-2.0427 |
0.005 |
984 |
Q9R0P5 |
Dstn |
Destrin |
3 |
15.15 |
0.7890 |
1.7844 |
2.2615 |
0.005 |
1189 |
Q9Z2D6 |
Mecp2 |
Methyl-CpG-binding protein 2 |
2 |
3.31 |
1.0342 |
0.6078 |
-1.7015 |
0.005 |
163 |
Q8BGQ7 |
Aars |
Alanine--tRNA ligase, Cytoplasmic |
8 |
6.71 |
1.0410 |
0.7817 |
-1.3316 |
0.006 |
747 |
Q61595 |
Ktn1 |
Kinectin |
3 |
1.58 |
1.0268 |
0.5136 |
-1.9992 |
0.008 |
1241 |
Q9CYR6 |
Pgm3 |
Phosphoacetylglucosamine mutase |
3 |
4.98 |
0.9864 |
0.7734 |
-1.2754 |
0.008 |
329 |
Q9D051 |
Pdhb |
Pyruvate dehydrogenase E1 component subunit beta |
5 |
10.03 |
0.7227 |
1.4883 |
2.0593 |
0.008 |
1420 |
Q3UBX0 |
Tmem109 |
Transmembrane protein 109 |
3 |
7.41 |
1.0633 |
0.6594 |
-1.6125 |
0.008 |
1745 |
Q8VDP6 |
Cdipt |
CDP-diacylglycerol--inositol 3- phosphatidyltransferase |
2 |
4.7 |
0.9876 |
1.6796 |
1.7006 |
0.009 |
1593 |
Q9WV54 |
Asah1 |
Acid ceramidase |
2 |
3.05 |
0.8656 |
1.3823 |
1.5969 |
0.010 |
732 |
Q60605 |
Myl6 |
Myosin light polypeptide 6 |
4 |
21.85 |
0.9320 |
0.3505 |
-2.6588 |
0.010 |
1069 |
Q9D883 |
U2af1 |
Splicing factor U2AF 35 kDa subunit |
2 |
8.79 |
0.7820 |
0.4190 |
-1.8663 |
0.010 |
553 |
Q68EF6 |
Begain |
Brain-enriched guanylate kinase-associated protein |
3 |
5.50 |
0.9216 |
0.4622 |
-1.9936 |
0.014 |
1104 |
P27671 |
Rasgrf1 |
Ras-specific guanine nucleotide-releasing factor 1 |
3 |
2.46 |
0.9780 |
0.6214 |
-1.5738 |
0.015 |
631 |
P15105 |
Glul |
Glutamine synthetase |
4 |
8.58 |
0.8174 |
1.4467 |
1.7698 |
0.016 |
667 |
Q9CXZ1 |
Ndufs4 |
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 |
2 |
12.00 |
1.0614 |
0.5591 |
-1.8983 |
0.016 |
558 |
Q8C8N2 |
Scai |
Protein SCAI |
3 |
7.10 |
0.8066 |
1.2477 |
1.5468 |
0.017 |
1272 |
Q9ES28 |
Arhgef7 |
Rho guanine nucleotide exchange factor 7 |
2 |
2.90 |
0.9912 |
0.5186 |
-1.9114 |
0.018 |
287 |
P63024 |
Vamp3 |
Vesicle-associated membrane protein 3 |
6 |
38.83 |
0.9981 |
0.5565 |
-1.7936 |
0.020 |
538 |
Q9CYZ2 |
Tpd52l2 |
Tumor protein D54 |
3 |
18.18 |
0.9264 |
0.4654 |
-1.9906 |
0.021 |
45 |
P60469 |
Ppfia3 |
Liprin-alpha-3 |
11 |
9.88 |
1.0726 |
0.8688 |
-1.2345 |
0.024 |
1608 |
O54724 |
Ptrf |
Polymerase I and transcript release factor |
2 |
4.59 |
1.1661 |
0.6941 |
-1.6800 |
0.024 |
1030 |
P51855 |
Gss |
Glutathione synthetase |
4 |
7.38 |
0.8774 |
0.5838 |
-1.5029 |
0.025 |
263 |
P12023 |
App |
Amyloid beta A4 protein |
6 |
6.75 |
1.0800 |
0.7106 |
-1.5198 |
0.026 |
601 |
Q8C854 |
Myef2 |
Myelin expression factor 2 |
2 |
3.89 |
1.0670 |
1.7657 |
1.6548 |
0.029 |
529 |
O35874 |
Slc1a4 |
Neutral amino acid transporter A |
3 |
7.52 |
0.7254 |
1.0378 |
1.4306 |
0.030 |
95 |
P02468 |
Lamc1 |
Laminin subunit gamma-1 |
9 |
5.41 |
0.9576 |
0.6145 |
-1.5582 |
0.031 |
50 |
Q9QYX7 |
Pclo |
Protein piccolo |
21 |
3.37 |
1.2671 |
0.8413 |
-1.5061 |
0.032 |
536 |
B1AXV0 |
Frrs1l |
DOMON domain-containing protein FRRS1L |
3 |
11.6 |
1.0615 |
1.2256 |
1.1545 |
0.033 |
1032 |
P31648 |
Slc6a1 |
Sodium- and chloride- dependent GABA transporter 1 |
3 |
3.84 |
1.3463 |
1.7726 |
1.3166 |
0.034 |
103 |
P09405 |
Ncl |
Nucleolin |
10 |
9.19 |
1.1258 |
0.6735 |
-1.6715 |
0.036 |
858 |
Q80VP1 |
Epn1 |
Epsin-1 |
2 |
2.44 |
0.9593 |
1.3059 |
1.3613 |
0.038 |
293 |
Q8CHU3 |
Epn2 |
Epsin-2 |
4 |
6.72 |
1.0502 |
0.6278 |
-1.6727 |
0.038 |
2185 |
Q9D8B7 |
Jam3 |
Junctional adhesion molecule C |
2 |
5.16 |
0.9084 |
0.5570 |
-1.6309 |
0.039 |
703 |
Q922D8 |
Mthfd1 |
C-1-tetrahydrofolate synthase |
2 |
2.67 |
0.8567 |
0.6992 |
-1.2252 |
0.040 |
199 |
Q80U49 |
Kiaa0284 |
Protein KIAA0284 |
7 |
4.70 |
1.0813 |
0.6964 |
-1.5528 |
0.041 |
543 |
P61089 |
Ube2n |
Ubiquitin-conjugating enzyme E2 N |
5 |
17.76 |
1.1432 |
0.8175 |
-1.3984 |
0.043 |
2209 |
Q61290 |
Cacna1e |
Voltage-dependent R-type calcium channel subunit alpha- 1E |
2 |
0.75 |
1.3296 |
0.8312 |
-1.5996 |
0.045 |
1157 |
Q8K010 |
Oplah |
5-oxoprolinase |
2 |
1.63 |
0.9406 |
1.3386 |
1.4231 |
0.048 |
630 |
P48320 |
Gad2 |
Glutamate decarboxylase 2 |
2 |
4.44 |
0.8542 |
0.4905 |
-1.7416 |
0.048 |
1444 |
Q924M7 |
Mpi |
Mannose-6-phosphate Isomerase |
3 |
4.96 |
1.1433 |
0.5007 |
-2.2834 |
0.049 |
Abbreviations = Accession No. is the UniProtKB protein code, % Cov = % Coverage (95 CI), FC = Fold Change, Cont = Control AVD = AVD-deficient