Table 1: Baseline patient's characteristics.
| Characteristic | All | Admission (24 hours) | Third day | Fifth day |
| Sample size, n | 978 | 978 | 624 | 289 |
| Age, median (IQR) | 51 (37-61) | 51 (37-61) | 51 (38-62) | 52 (40-63) |
| Male, n (%) | 471 (48.2%) | 471 (48.2%) | 297 (47.6%) | 137 (47.4%) |
| Admission type, n (%) | ||||
| Neurological | 292 (29.9%) | 292 (29.9%) | 235 (37.7%) | 145 (50.2%) |
| Neurosurgical | 686 (70.1%) | 686 (70.1%) | 389 (62.3%) | 144 (49.8%) |
| Length of ICU stay, median (IQR) | 4 (2-8) | 4 (2-8) | 6 (4-13) | 11 (6-20) |
| Length of hospital stay, median (IQR) | 13 (8-26) | 13 (8-26) | 17 (10-31) | 27 (15-44) |
| Severity scores, median (IQR) | ||||
| APACHE II | 10 (7-14) | 10 (7-14) | 12 (8-15) | 13 (10-17) |
| SAPS 3 | 35 (25-46) | 35 (25-46) | 39 (28-52) | 46 (32-56) |
| SOFA | 2 (1-4) | 2 (1-4) | 2 (1-5) | 3 (1-6) |
| Hospital mortality, n (%) | 62 (6.3%) | 62 (6.3%) | 45 (7.2%) | 29 (10%) |