Table 2: Summary of seven insets in Figure 4. Other unlisted parameters used in all the seven cases are: DECS = 367 µm2/s, DMEM = 108 µm2/s, ρ = 1 g/ c m 3 , µ = 0.09 cp.

Numerical error analysis, symbols referred to Eq. (7)-(15) Description
r21

r32

Relative recovery Time to reach steady state
Data point in Figure 4 L (µm) H (µm) DCHM (µm2/s) V0 (µm/s) r ext 21

rr1

rr2

rr3

p r ext 21

r a 21

e a 32

(%)
GCI21

GCI32

(%)
s s ext 21

ss1

ss2

ss3

(s)
p r ext 21

r a 21

e a 32

(%)
GCI21

GCI32

(%)
(1) 60 60 3000 120 1.30 0.672 3.20 9.5 13.1 2.506 5.34 14.2 6.7 Relative recovery predictable by Eq. (6). The diffusivity
is compatible to the flow speed. Microdialysis is in an optimal
condition in which analytes are recovered the most efficiently.
1.21 0.608 13.9 35.4 2.151 16.5 1.8
0.524 20.9 2.506 2.6
0.394 2.440
(2) 30 30 800 500 1.23 0.182 17.85 0.0 0.0 0.959 3.12 11.6 18.1
1.27 0.182 0.49 0.49 0.878 13.1 8.4
0.183 27.9 0.959 7.4
0.131 1.031
(3) 200 60 1200 1200 1.22 0.055 3.84 9.9 13.6 0.977 14.88 2.6 0.2
1.22 0.049 12.6 33.5 0.952 2.7 3.4
0.043 30.2 0.977 47.7
0.030 1.443
(4) 30 14 1200 300 1.16 0.335 1.16 1.3 1.8 0.684 10.94 26.8 11.5 Fast diffusivity and slow perfusion. Analytes spend
longer than necessary in the chamber, resulting in
a higher recovery.
1.26 0.331 3.3 6.1 0.501 36.5 1.7
0.320 27.8 0.684 15.6
0.231 0.791
(5) 60 60 3000 600 1.22 0.478 3.47 9.9 13.8 2.146 2.93 15.3 28.3
1.22 0.430 11.1 31.2 1.817 18.1 13.6
0.383 24.3 2.146 8.5
0.289 1.964
(6) 15 15 600 400 1.23 0.090 14.11 0.1 0.15 0.379 4.14 14.2 15.4 Relatively fast perfusion causes a low relative recovery.
1.24 0.090 2.1 2.71 0.325 16.6 5.6
0.092 43.2 0.379 6.4
0.052 0.403
(7) 50 40 760 2 1.18 0.612 2.59 10.6 14.8 2.481 6.64 3.1 2.0 Analytes are recovered under a nearly stationary flow.
1.21 0.547 6.3 24.1 2.561 3.0 0.7
0.513 12.2 2.483 1.4
0.450 2.449