Table 2: Fentanyl consumption in the 2 cohorts. Values are displayed as the mean and median (quartiles) with P-values (group comparison by Mann–Whitney U-tests).

Cumulative Fentanyl dose (mcg)

NOL-guided group

(prospective cohort)

(n=34)

Control group

(retrospective cohort)

(n=36)

P-value

(Mann-Whitney)

Mean

445.6

562.5

0.005

Median

450

600

25%–75% percentiles

300-600

450-600

Min.

150

300

Max.

750

900

Abbreviations: NOL: Nociception Level; CI: Confidence interval.