Table 3: Correlation between Spermidine and Neuroimaging and clinical data.
|
Variables |
r |
P |
|
n = 43 |
||
|
Total CNS Vol |
-0.054 |
0.75 |
|
Ventricular CSF Vol |
0.123 |
0.48 |
|
Subarachnoid Vol |
-0.168 |
0.33 |
|
Hippocampal Vol |
0.07 |
0.7 |
|
WM Hyper intensity Vol |
-0.142 |
0.42 |
|
Apoe4 |
0.209 |
0.19 |
|
n = 24 |
||
|
hepcidin |
0.312 |
0.15 |
|
Hepcidin (MMSE: 8-19) |
0.604 |
0.02 |
|
Hepcidin (CDR-SOB: 12-6) |
0.601 |
0.03 |
|
Ferritin |
0.221 |
0.33 |
|
Iron |
-0.174 |
0.45 |
|
Transferrin |
-0.314 |
0.26 |
|
% saturation |
0.148 |
0.53 |
|
Aβ 40 |
-0.13 |
0.61 |
|
Aβ 42 |
-0.0467 |
0.83 |
Abbreviations: AD: Alzheimer's disease, Aβ: amyloid beta, CDR-SOB: clinical dementia rating scale sum of boxes, MMSE: mini mental state examination, WM: white matter