Table 2:Lists current applications of NPs in biology and medicine.
NPs | Applications | Safety/Adverse effects | References |
---|---|---|---|
Gold colloid | Medical diagnostics
Drug/gene delivery Pharmaceuticals |
LD: Relatively safe
HD: Cytotoxicity, kidney and liver damage |
[180-182] |
Silver colloid | Similar to Gold
Antimicrobial agents Clothing odor resistance |
LD: Oxidative stress
HD: Neurotoxicity and liver damage, antibacterial |
[183-185] |
TiO2 | Antimicrobial paint, tooth paste and cosmetics | Autistic disorders, epilepsy
Alzheimer's like plaques |
[186-188] |
Fe | Environmental remediation | Oxidative stress, inflammation liver toxicity | [189,190] |
Fe2O3 | Magnetic nanoparticle - contrast agents for tumor imaging | Oxidative stress, membrane leakage of LDH, DNA damage, inflammation | [37,191] |
CNTs | Diagnostics
Consumer electronics Sports equipment |
Mitochondrial toxicity, cell
cycle arrest, liver and lungs damage, frustrated phagocytosis |
[192-195] |
Fullerenes | Drug delivery | Oxidative stress, inflammation
Liver damage |
[196,197] |
Linear polymers | Drug delivery | LD: Relatively safe
HD: CNS and liver damage s |
[198,199] |
Dendrimers | Drug delivery | Relatively safe. Some dendrimers may mimic body proteins and enzymes | [200-202] |